Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
50 patients around the world
Available in Mexico
The goal of this clinical trial is to learn if melatonin works to treat comorbid insomnia in
adults with OSA and nocturnal non-dipping blood pressure pattern.
The main question it aims to answer is:
Does melatonin maintain sleep during night and recover the dipping blood pressure pattern?
Participants will:
- Take melatonin or the habitual treatment every day for one month
- Visit the clinic 11 times for one month
- Keep a diary of their symptom and activities and use twice a 24 h ambulatory blood
pressure monitoring (ABPM), attend two overnight polysomnography studies, and use an
actigraph every day for 2 weeks.
Researchers will compare melatonin to the habitual treatment to see if melatonin works to
treat insomnia and recover the dipping blood pressure pattern.
The medical problems that participants would have when taking melatonin are:
- changes in blood pressure and cholesterol
- Increased risk of contracting immune system disorders
- Possible increased risk of liver damage.
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
1Research sites
50Patients around the world
This study is for people with
Sleep disorders
Sleep apnea
Requirements for the patient
To 60 Years
All Gender
Medical requirements
Polisomnographic diagnosis of Obstructive Sleep Apnea
Non-dipping blood pressure on Ambulatory blood pressure monitoring (ABPM):
Use of sleep or psychiatric medication
Use of Positive Airway Pressure (CPAP or Bipap)
Neurologic or psychiatric disorder
Sites
Instituto Nacional de Ciencias Médicas y Nutrición Dr. Salvador Zubirán
Recruiting
Vasco de Quiroga 15, Belisario Domínguez Secc 16, 14080 Ciudad de México
StudyMEBP-OSA
SponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran