Last updated 2 years ago

Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study

100 patients around the world
Available in Mexico
The study included 208 teeth with yellow-brown or creamy-white defects in children aged 6-12 years who were newly diagnosed with MIH with no substance loss or caries or prior restorative treatment. The children will be randomly divided into the experiment groups: control (oral hygiene motivation only), fluoride varnish, clinpro white Varnish and pastes containing CPP-ACP and followed up for 24 months. The evaluations will be made based on the ICDAS criteria and the measurements which were performed using the laser fluorescence method (DIAGNOdent, KaVo, Biberach, Germany) in the follow-ups.
Universidad Nacional Autonoma de Mexico
100Patients around the world

This study is for people with

Molar Incisor Hypomineralization

Requirements for the patient

To 12 Years
All Gender

Medical requirements

Children between 6 to 12 years.
They live in the selected study area.
Have at least one permanent incisor or molar with mild or moderate MIH (creamy white and/or yellow or brown opacities).
That their parents authorize participation in the study through informed consent.
No proven or suspected allergy and/or sensitivity to milk protein, as it is a component of the CPP-ACP product.
Defects in enamel development related to syndromes, dental fluorosis, amelogenesis imperfecta, dentinogenesis imperfecta.
Presence of orthodontic appliances.
Teeth with MIH with restorations, or severe MIH (affected enamel develops post-eruptive enamel breakdown), or carious lesions classified as score >0 according to the ICDAS.
Children who do not show cooperation in the use of remineralizing agents.
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