Last updated 4 months ago

Effect of Triticum Aestivum on Appetite, Ghrelin, Leptin, Adiponectin Hormonal Axis in Patients With Obesity

38 patients around the world
Available in Mexico
A double-blind clinical trial is proposed, with two parallel groups, with random assignment and group control. The universe of the sample will be patients with a diagnosis of obesity, residents of the Guadalajara Metropolitan Area, who agree to participate by signing informed consent and can go to the Biomedical Unit 02 of the Mexican Institute of Social Security. Two parallel groups, with randomization by software using envelopes, will require a total of 38 patients, which will be distributed as follows: 1) A group of 19 patients with a diagnosis of obesity without pharmacological or surgical treatment, who will receive 500 mg capsules with lyophilized Triticum aestivum orally every 12 hours for 120 days, and 2) A group of 19 patients with a diagnosis of obesity without pharmacological or surgical treatment, who will receive 500 mg capsules of placebo (calcined magnesia) orally every 12 hours for 120 days.
Coordinación de Investigación en Salud, Mexico
38Patients around the world

This study is for people with

Obesity

Requirements for the patient

To 50 Years
All Gender

Medical requirements

People of any sex (eumenorrheic women with mechanical or definitive contraceptive method without hormonal treatment).
Age from 30 to 50 years old.
Residents of the metropolitan area of Guadalajara.
Signed informed consent form.
People with a diagnosis of obesity (BMI ≥30 - 39.9 kg/m2), stable body weight within the 3 months prior to the start of the study.
Diagnosis of diabetes and dyslipidemia.
Diagnosis of anxiety and/or depression.
History of: liver disease, chronic kidney disease, thyroid disease, cancer.
Antidiabetic treatment, lipid-lowering, food supplements, antidepressants, corticosteroids.
Acute infectious processes
Alcoholism and/or active smoking in any intensity within the 12 months prior to the start of the study.
Suspected or confirmed pregnancy or breastfeeding.
History of drug intake.
Recent surgery (<3 months)
Carrying a pacemaker, or any other bioelectronic or metallic element.
Excessive sedentary lifestyle defined as physical activity less than the equivalent of 15 minutes of walking per day.
Excessive exercise, defined as physical activity equivalent to running for 60 minutes per day.
Intake of anorexigenic drugs, hypolipidemic drugs or drugs with effect on body weight.
History of any type of cancer, hyperthyroidism, hypothyroidism, renal disease, liver disease and pancreatic disease.
History of hypersensitivity to the study drug (gluten).
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