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A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

1000 patients around the world

Available in Brazil, Mexico, Puerto Rico, United States, Spain

Eli Lilly and Company

18Research sites

1000Patients around the world

This study is for people with

Depression

Major depression

To 75 Years

All Gender

: Meet the diagnostic criteria for major depressive disorder.
Are on stable standard of care medication for major depressive disorder.
Are reliable and willing to make themselves available for the duration of the study and attend required study visits, and are willing and able to follow study procedures as required, such as.
Self-inject study intervention.
Store and use the provided blinded study intervention, as directed.
Maintain electronic and paper study diaries, as applicable, and.
Complete the required questionnaires.

: Have a lifetime history or current diagnosis of the following.
Schizophrenia spectrum or other psychotic disorder.
Bipolar disorder.
Borderline personality disorder, or.
Any eating disorder.
Have type 1 diabetes mellitus, or a history of.
Ketoacidosis, or.
Hyperosmolar state or coma.
Evidence of moderate or severe substance or alcohol use disorder within 180 days of screening.
Are actively suicidal or deemed a significant risk for suicide.
Have participated in a clinical study and received active treatment, or unknown if they received active treatment, within 90 days or 5 half-lives (whichever is longer) before screening.

Centro Paulista de Investigação Clínica - CEPIC

R. Moreira e Costa, 342 - Ipiranga, São Paulo - SP, 04266-010

INTEGRAL Pesquisa e Ensino

Av. da Saudade, 2147 - Parque Res. Friozi, Votuporanga - SP, 15501-405, Brasil

Instituto De Pesquisa Clinica de Campinas - Ipecc

Rua Oswaldo Oscar Barthelson, 1209 - Jardim Pauliceia, Campinas - SP, 13060-080

Cline Research Center

Praça São Paulo da Cruz, 50 - Cabral, Curitiba - PR, 80030-000

Clínica Neurologica e Neurocirurgica de Joinville Ltda

Rua Miguel Couto, 133 – Anita Gabribaldi – Joinville/SC – CEP 89202-190

Hospital das Clínicas Universidade Federal de Pernambuco - UFPE

Av. Prof. Moraes Rego, 1235 - Cidade Universitária, Recife - PE, 50670-901

CEMEC - Centro Multidisciplinar de Estudos Clínicos

R. Silva Jardim, 187 - 63 - Centro, São Bernardo do Campo - SP, 09715-090, Brazil

Fundação Faculdade Regional de Medicina de São José do Rio Preto

Av. Brg. Faria Lima, 5544 Sao Jose do Rio Preto - Estado de São Paulo 15090-000

PSEG Trials - Centro de Pesquisa Clinica S.A.

R. Borges Lagoa, 1060 - 133 134 135 - Vila Clementino, São Paulo - SP, 04038-002, Brazil

Cedoes - Pesquisa e Diagnóstico

R. João da Silva Abreu, 78 - Praia do Canto, Vitória - ES, 29055-450

StudyRENEW-MDD- 2

SponsorEli Lilly and Company

Study typeInterventional

Conditions

Major depression

Requirements

To 75 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT07775300