Last updated 36 days ago
Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.
36 patients around the world
Available in Mexico
This prospective, consecutive, interventional, longitudinal, case series study includes
patients with aqueous-deficient dry eye disease who have inferior punctal occlusion. The
study aims to evaluate the effect of superior lacrimal punctal occlusion with a plug dry
eye symptoms and signs. Assessments will be performed at baseline and at 2 weeks, 4
weeks, 3 months, and 6 months following superior punctal occlusion
Universidad Autonoma de Nuevo Leon
1Research sites
36Patients around the world
This study is for people with
Dry eye syndrome
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Patients of both sexes.One or both eyes may be included.Inferior lacrimal punctum occluded (with a punctal plug or cauterization), clinically sealed under slit-lamp examination.Functional superior lacrimal punctum.Aqueous-deficient dry eye (such as Sjögren's disease, graft-versus-host disease, or primary dry eye disease.).Age >18 years.OSDI score >13 and one of the following signs: Tear film markers (Fluorescein tear break up-time <5, First non-invasive tear breakup time <10, Schirmer test without anesthesia <10 mm, Schirmer test with anesthesia <10 mm), Ocular surface markers (corneal staining >5 spots or conjunctival staining >9 spots).
- Active ocular surface infection.Patients who are unwilling to participate or to provide written informed consent.
Sites
Oftalmología, Hospital Universitario, Fac. Medicina UANL
Recruiting
SponsorUniversidad Autonoma de Nuevo Leon
Study typeInterventional
Conditions
Dry eye syndrome
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT07571330
