Last updated 42 days ago

Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.

100 patients around the world

Available in Brazil

Menzies School of Health Research

100Patients around the world

This study is for people with

Malaria

G6PD deficiency

Requirements for the patient

From 18 Years

All Gender

Medical requirements

: P. vivax peripheral parasitaemia (mono-infection).
G6PD intermediate or deficient status (G6PD activity 30-<70% or ≤30% of the adjusted male median as determined by the Standard G6PD (SDBioline, ROK)).
Fever (temperature ≥37.5⁰C) or history of fever in the preceding 48 hours.
Age ≥18 years.
Haemoglobin at presentation ≥8g/dl.
Written informed consent.
Living in the study area and willing to be followed for six months.

: Danger signs or symptoms of severe malaria.
Pregnant or lactating females.
Regular use of drugs with haemolytic potential.
Known hypersensitivity to any of the study drugs.

SponsorMenzies School of Health Research

Study typeInterventional

Conditions

MalariaG6PD deficiency

Requirements

From 18 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT07468513