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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

1980 patients around the world

Available in Puerto Rico, Argentina, United States, Brazil

Eli Lilly and Company

29Research sites

1980Patients around the world

This study is for people with

Obesity

From 18 Years

All Gender

: Have Body Mass Index (BMI) at screening of the following.
30 kilogram per square meter (kg/m2) OR.
27 kg/m2 with at least one of the following weight-related health conditions at screening.
High blood pressure.
Dyslipidemia.
Obstructive sleep apnea.
Heart disease.
Have a stable body weight (<5% body weight change) for 90 days prior to screening.
Have a history of at least one self-reported unsuccessful dietary effort to reduce body weight.

: Have a prior or planned surgical treatment for obesity.
Liposuction, cryolipolysis, or abdominoplasty allowed if performed >1 year before screening.
Have a prior or planned endoscopic procedure and/or device-based therapy for obesity.
Prior device-based therapy acceptable if device removal was more than 6 months prior to screening.
Have type 1 diabetes or type 2 diabetes.
Have had within 90 days prior to screening.
Heart attack.
Stroke.
Coronary artery revascularization.
Unstable angina.
Hospitalization due to congestive heart failure.
Have a history or diagnosis of New York Heart Association Functional Classification Class IV congestive heart failure.
Have taken medications or alternative remedies intended for weight loss within 90 days of screening.

Centro Médico Saavedra

Av. Ruiz Huidobro 4693, C1430 Cdad. Autónoma de Buenos Aires, Argentina

Instituto de Especialidades de la Salud Rosario Clínica del Tórax

España 931, Rosario, Santa Fe

Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Médica - Rosario, Santa Fe

Rioja 2926, Rosario, Santa Fe

Centro Médico Viamonte SRL - CABA, Buenos Aires

Av. Córdoba 2019, CABA, Buenos Aires

Centro de Investigaciones Médicas Tucumán

Lavalle 506, T4000 San Miguel de Tucumán, Tucumán, Argentina

Instituto de Investigaciones Clínicas Córdoba

Dean Funes 1161, Córdoba

CIPREC Centro de Investigación y Prevención Cardiovascular - CABA

Av. Pueyrredón 1746 2° A, C1119 Cdad. Autónoma de Buenos Aires, Argentina

Laboratorio LAHT - Laboratorio de Hemostasia y Trombosis

Blvd. Oroño 1425, S2000 Rosario, Santa Fe, Argentina

Centro Modelo de Cardiología SRL - Tucumán

Laprida 554, San Miguel de Tucumán

Fundación Centro de Salud e Investigaciones Médicas (CESIM)

Urquiza 646, Santa Rosa, La Pampa

StudyENLIGHTEN-1

SponsorEli Lilly and Company

Study typeInterventional

Conditions

Obesity

Requirements

From 18 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT07321886