Last updated 3 days ago
A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)
975 patients around the world
Available in Spain, United States, Brazil, Argentina
Merck Sharp & Dohme LLC
12Research sites
975Patients around the world
This study is for people with
Hyperlipidemia
Requirements for the patient
To 64 Years
All Gender
Medical requirements
- Has either not received lipid-lowering therapy or has not received certain LLTs within a specified time period prior to the study.
- Has a history of homozygous familial hypercholesterolemia, compound heterozygous FH, or double heterozygous FH.Had a heart failure hospitalization within 3 months before Screening.Is unwilling to take a statin and has a history of statin-associated muscle symptoms or other statin-related AEs to any statin and dose and is known to be intolerant to 1 or more statins.Has a history of any of the following conditions: Myopathy, myositis, rhabdomyolysis, or unexplained muscle pain; Muscular or neuromuscular disease; Neuropathy, fibromyalgia, or chronic pain; or Has a personal or family history of hereditary muscular disorders.Has active or chronic hepatobiliary or hepatic disease.Has known human immunodeficiency virus infection.Is undergoing or previously underwent an LDL-C apheresis program within 3 months before Screening or plans to initiate an LDL-C apheresis program.Has received any medication that may interact with rosuvastatin within 5 half-lives prior to Screening or is planning to initiate such treatment.
Sites
Centro Médico Maffei - CABA, Buenos Aires
Recruiting
Instituto de Investigaciones Clínicas (IIC) - Rosario
Recruiting
Instituto Médico de la Fundación Estudios Clínicos - Rosario
Recruiting
CIPREC Centro de Investigación y Prevención Cardiovascular - CABA
Recruiting
Instituto de Investigaciones Clínicas Mar del Plata
Recruiting
Instituto de Cardiología Juana Francisca Cabral - Corrientes
Recruiting
Centro Especialidades Médicas SRL (CEMEDIC)
Recruiting
Centro de Pesquisas em Diabetes e Doenças Endócrino-Metabólicas / Clinica Popular Endocrinologia
Recruiting
Clínica do Coração
Recruiting
Fundação Faculdade Regional de Medicina de São José do Rio Preto
Recruiting
StudyMK-0616-037
SponsorMerck Sharp & Dohme LLC
Study typeInterventional
Conditions
Hyperlipidemia
Requirements
To 64 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT07216482
