Last updated 5 days ago
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
800 patients around the world
Available in United States, Mexico
Eli Lilly and Company
6Research sites
800Patients around the world
This study is for people with
Osteoarthritis
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Have a body mass index (BMI) of 27 kilograms per square meter (kg/m2) or higher at screening.Have tried at least once to lose weight through diet but were unsuccessful.Have osteoarthritis of the knee and at least one of the following conditions.Be over 50 years old.Have morning knee stiffness that lasts about 30 minutes.Have a crackling or grinding sound or feeling in the knee.
- Have gained or lost more than 11 pounds within 90 days prior to screening.Have had a surgery for obesity or plan to have one in the next 18 months.Have an active knee infection.Have type 1 diabetes, type 2 diabetes, or any other type of diabetes.Have had a recent heart condition or New York Heart Association Functional Classification Class IV congestive heart failure.Have used any glucagon-like peptide-1 (GLP-1) receptor agonist medication within 180 days of screening.
Sites
Köhler & Milstein Research
Investigación y Biomedicina de Chihuahua
Centro de Estudios de Investigación Metabólica y Cardiovascular SC
Centro Médico del Ángel
IMED Internal Medicine Clin Trials S.C.
Clínica García Flores
StudyATTAIN-OA PAIN
SponsorEli Lilly and Company
Study typeInterventional
Conditions
Osteoarthritis
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT07153471
