Available in Brazil
This study will evaluate the effectiveness of a 10% Biosilicate® solution as a
desensitizing agent in MIH teeth in children, compared to Fluoride varnish (Duraphat®
Colgate, Brazil). The children included in the study will be subdivided into three
randomized treatment options, which are: Group 1: Fluoridated varnish (Duraphat® Colgate,
Brazil); Group 2: Biosilicate® 10%. The randomization sequence will be generated using
the envelope method. A numerical sequence (1 and 2) will be printed, which will
correspond sequentially to the three groups (GI and GII). The numbers will be placed in
envelopes with the same characteristics and then sealed. The implementation of the random
allocation sequence will be carried out by a single researcher, who will use the
previously sealed envelopes along with the numbers corresponding to the treatments to be
administered. As each child is included in the study, an envelope will be labeled with
the child's name and will only be opened by the operator before the start of the
treatment. Children with the potential for inclusion in the research will be referred for
clinical examination in the mobile dental unit (Dental Case), and those with at least one
first permanent molar affected by MIH and reporting hypersensitivity, with or without
structure loss, will be invited to participate. The complaint of sensitivity will be
confirmed by applying a 1-second air blast at a distance of 1 centimeter from the
occlusal surface of the tooth; a score of 2 or 3 on the Schiff Cold Air Sensitivity Scale
(SCASS) will be considered a positive result.
1Research sites
42Patients around the world