Last updated 26 days ago

BIOSILITACE AS A DESENSITIZING AGENTIN HMI

42 patients around the world
Available in Brazil
This study will evaluate the effectiveness of a 10% Biosilicate® solution as a desensitizing agent in MIH teeth in children, compared to Fluoride varnish (Duraphat® Colgate, Brazil). The children included in the study will be subdivided into three randomized treatment options, which are: Group 1: Fluoridated varnish (Duraphat® Colgate, Brazil); Group 2: Biosilicate® 10%. The randomization sequence will be generated using the envelope method. A numerical sequence (1 and 2) will be printed, which will correspond sequentially to the three groups (GI and GII). The numbers will be placed in envelopes with the same characteristics and then sealed. The implementation of the random allocation sequence will be carried out by a single researcher, who will use the previously sealed envelopes along with the numbers corresponding to the treatments to be administered. As each child is included in the study, an envelope will be labeled with the child's name and will only be opened by the operator before the start of the treatment. Children with the potential for inclusion in the research will be referred for clinical examination in the mobile dental unit (Dental Case), and those with at least one first permanent molar affected by MIH and reporting hypersensitivity, with or without structure loss, will be invited to participate. The complaint of sensitivity will be confirmed by applying a 1-second air blast at a distance of 1 centimeter from the occlusal surface of the tooth; a score of 2 or 3 on the Schiff Cold Air Sensitivity Scale (SCASS) will be considered a positive result.
University of Sao Paulo
1Research sites
42Patients around the world

This study is for people with

Molar Incisor Hypomineralization

Requirements for the patient

To 12 Years
All Gender

Medical requirements

Children of both sexes, aged between 6 and 12 years.
Children who have at least one first permanent molar with Molar-Incisor Hypomineralization, showing distinct white or cream opacity (score 21), yellowish or brown opacity (score 22), and/or post-eruptive enamel fracture (score 3), and presence of painful sensitivity when stimulated, with a score of 2 or 3 as evaluated using the SCASS scale.
Children without systemic and/or cognitive impairments.
Previous use of desensitizing therapy in the last 6 months.
Use of analgesic and anti-inflammatory medications during the previous 3 days.
Use of orthodontic appliances.
Teeth with extensive restorative procedures, such as stainless steel crowns, which prevent the assessment of painful sensitivity.
Teeth with amelogenesis imperfecta or dentinogenesis imperfecta.
Children with systemic and/or cognitive impairments.

Sites

Faculdade de Odontologia de Ribeirão Preto - USP
Av. do Café - Ribeirão Preto, SP, Brazil
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