Last updated 41 days ago

Mandibular Advancement Devices for Reflux in Obstructive Sleep Apnea

40 patients around the world

Available in Brazil

Tuiuti University of Paraná

1Research sites

40Patients around the world

This study is for people with

Gastrointestinal Disorders

Gastroesophageal Reflux Disease

To 65 Years

All Gender

: Adults aged 18 to 65 years.
Clinical diagnosis of obstructive sleep apnea (OSA) confirmed by polysomnography type I.
Presence of nocturnal gastroesophageal reflux symptoms.
Not currently using CPAP therapy.
Dentate individuals able to wear oral devices.
Able and willing to comply with the study protocol.
Provided written informed consent.

: Severe OSA (Apnea-Hypopnea Index > 30).
Current or recent use of proton pump inhibitors or other anti-reflux medications.
Neurological or neuromuscular disorders.
Use of removable dental prostheses (partial or total).
Prior surgeries for apnea or reflux.
Known allergy or intolerance to dental acrylic materials.
Inability to attend follow-up visits or complete questionnaires.

Universidade Tuiuti do Paraná - Centro de Diagnostico e Tratamento da Articulação Têmporo Mandibular – CDATM

R. Padre Ladislau Kula, 395 - Santo Inácio, Curitiba - PR, 82010-210, Brazil

StudyMAD-ROSA

SponsorTuiuti University of Paraná

Study typeInterventional

Conditions

Gastroesophageal Reflux Disease

Requirements

To 65 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT07049315