Last updated 12 days ago
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
974 patients around the world
Available in Puerto Rico, Argentina, United States
Eli Lilly and Company
10Research sites
974Patients around the world
This study is for people with
Arterial hypertension
Obesity
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Has systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg (if DBP criteria alone is met, SBP must be ≥130 mmHg) at screening (Visit 1).Has SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg (if DBP criteria alone is met, SBP must be ≥130 mmHg) at week 0 (Visit 3).Untreated for hypertension, or on stable antihypertensive medications ≥ 30 days prior to Visit 1.Have a body mass index (BMI) ≥ 25 kg/m².
- Has SBP ≥170 mmHg and/or DBP ≥110 mmHg at Visit 1 or at Visit 3.Has known secondary causes of hypertension.Have heart failure with reduced ejection fraction (HFrEF) diagnosis.Have had any of the following conditions within 90 days prior to screening.hospitalization for hypertension or for congestive heart failure.acute coronary syndrome or acute myocardial infarction.cerebrovascular accident (stroke).Have type 1 diabetes (T1D).Have acute or chronic hepatitis, including a history of autoimmune hepatitis.
Sites
Instituto de Investigaciones Clínicas Córdoba
CIPREC Centro de Investigación y Prevención Cardiovascular - CABA
Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Médica - Rosario, Santa Fe
Centro de Investigaciones Clínicas Baigorria
INECO Neurociencias Oroño - Rosario
Instituto Médico Especializado (IME)
Centro Especialidades Médicas SRL (CEMEDIC)
Centro Médico Santa María de la Salud
Dorado Medical Complex
Puerto Rico Medical Research Center
SponsorEli Lilly and Company
Study typeInterventional
Conditions
Arterial hypertensionObesity
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT06948422
