Last updated 14 days ago

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

905 patients around the world

Available in Puerto Rico, Brazil, Argentina, United States, Mexico

Eli Lilly and Company

24Research sites

905Patients around the world

This study is for people with

Diabetes

Diabetes mellitus type 1

Obesity

From 18 Years

All Gender

: Have type 1 diabetes and on insulin treatment for at least one year prior to screening.
Have an HbA1c value of 7.0% to 10.5% inclusive, at screening.
Have a body mass index (BMI) of ≥25 kilograms per square meter (kg/m2) at screening.
Are of stable weight for at least 90 days prior to screening and agree to not start an intensive diet or exercise program during the study.

: Have experienced two or more events requiring hospitalization due to poor glucose control (hyperglycemia or diabetic ketoacidosis (DKA)) during the period of 180 days prior to screening and until randomization.
Have experienced one or more events of severe hypoglycemia during the period of 90 days prior to screening and until randomization.
Are currently receiving or planning to receive treatment for diabetic retinopathy and/or macular edema.
Have had chronic or acute pancreatitis.
Have used any weight loss drugs or alternative remedies, including herbal or nutritional supplements, within 90 days prior to screening.

Centro de Investigaciones Metabólicas (CINME) S.A. - CABA, Buenos Aires

Viamonte, Cdad. Autónoma de Buenos Aires, Argentina

Instituto de Investigaciones Clínicas Córdoba

Dean Funes 1161, Córdoba

CIPREC Centro de Investigación y Prevención Cardiovascular - CABA

Av. Pueyrredon 1746, CABA, Buenos Aires

Instituto Médico de la Fundación Estudios Clínicos - Rosario

Italia 428, Rosario - Santa Fe

Centro de Diagnóstico y Rehabilitación - CEDIR

SAN MARTIN 3169 – Santa Fe, Santa Fe. CP 3000

Investigaciones Médicas IMOBA SRL

Viamonte 2168, C1056ABH Cdad. Autónoma de Buenos Aires, Argentina

Centro de Investigaciones Médicas Mar del Plata SRL

Av. Colón 3083, Mar del Plata, Buenos Aires

Consultorio de Investigación Clinica EMO SRL

Eduardo Acevedo 42, CABA, Buenos Aires

Centro Médico Privado San Vicente Diabetes - Córdoba

Entre Ríos 2977, Córdoba

Fundación Centro de Salud e Investigaciones Médicas (CESIM)

Urquiza 646, Santa Rosa, La Pampa

StudySURPASS-T1D-1

SponsorEli Lilly and Company

Study typeInterventional

Conditions

Diabetes mellitus type 1Obesity

Requirements

From 18 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT06914895