Last updated 17 days ago

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

1088 patients around the world

Available in Puerto Rico, Colombia, Chile, Mexico

Takeda

15Research sites

1088Patients around the world

This study is for people with

Arthritis

Psoriasic arthritis

From 18 Years

All Gender

: The participant is aged 18 years or older at the time of signing the informed consent form (ICF).
The participant has had signs and symptoms consistent with PsA for at least 3 months.
The participant meets the Classification Criteria for Psoriatic Arthritis (CASPAR criteria).
The participant has active arthritis as shown by a minimum of >=3 tender joints in TJC68 and >=3 swollen joints in SJC66 at the screening and baseline (Day 1) visits.
The participant has at least 1 active lesion of plaque PsO >=2 cm in diameter, or any nail or nail bed changes characteristic of PsO.
The participant has had at least one of the following.
Inadequate response to a nonsteroidal anti-inflammatory drug (NSAID), OR.
Inadequate response to a conventional synthetic disease-modifying antirheumatic drug (csDMARD).

: The participant has other disease(s) that might confound the evaluations of benefit of zasocitinib therapy, including but not limited to rheumatoid arthritis, axial spondyloarthritis, systemic lupus erythematosus, Lyme disease, gout, or fibromyalgia.
The participant has a concomitant comorbid skin condition that, in the opinion of the investigator, would interfere with the study assessments, such as evidence of non-plaque PsO (erythrodermic, pustular, predominately guttate PsO, inverse, or drug-induced PsO).

Clínica Dermacross S.A. - Vitacura - Santiago

Av. Manquehue Norte 2051 C, Vitacura, Metropolitana, 7640881

Centro Internacional de Estudios Clínicos - CIEC

Calle Manzano 343, Oficina 410-411, Comuna de Recoleta, Región Metropolitana, 8420383

CTR Estudios Clínicos

Av. Providencia #1208, Oficina 209, Santiago

Centro de Estudios Reumatológicos

Av. Salvador 960, 7501126 Providencia, Región Metropolitana, Chile

SERVIMED S.A.S.

Calle 51 No 34-17 Consultorio 208 - Bucaramanga

Centro Integral de Reumatología del Caribe Circaribe SAS

Cl. 71 #41 - 46, Nte. Centro Histórico, Barranquilla, Atlántico

Fundación Santa Fe de Bogotá

calle 119 #7 75, Bogotá

CIREEM SAS (Centro de Investigación en Reumatología y Especialidades Médicas) - Bogotá

Cra 12 No. 97-32, Of. 201-301-404, Bogotá

Preventive Care S.A.S.

Carrera 1A N°11 - 130 Oficina 109 – 205 Chía

Centro de Investigación en Artritis y Osteoporosis

Calzada de las Américas # 430 Col Cuauhtémoc sur, Mexicali Baja California 21200

SponsorTakeda

Study typeInterventional

Conditions

Psoriasic arthritis

Requirements

From 18 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT06671483