Last updated 30 days ago

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

406 patients around the world
Available in Argentina, Puerto Rico, Brazil
Karuna Therapeutics
4Research sites
406Patients around the world

This study is for people with

Alzheimer disease

Requirements for the patient

To 90 Years
All Gender

Medical requirements

Patients who are 55 to 90 years of age, inclusive, at the time of Screening (Visit 1).
Patients who are diagnosed with possible AD or probable AD.
Patient must have a magnetic resonance imaging (MRI) or computed tomography (CT) scan of the brain taken during or subsequent to the onset of dementia to rule out other central nervous system (CNS) disease that could account for the dementia syndrome.
Patient must have a history of psychotic symptoms for at least 2 months prior to Screening (Visit 1).
Other protocol-defined criteria apply.
Psychotic symptoms that are primarily attributable to a condition other than the AD causing the dementia.
History of major depressive episode with psychotic features during the 12 months prior to Screening, or history of bipolar disorder, schizophrenia, or schizoaffective disorder.
Patients are not able to participate if they have certain safety concerns, including certain laboratory test irregularities.
Other protocol-defined criteria apply.

Sites

Santa Cruz Behavioral PSC - Puerto Rico
Recruiting
73 Cll Santa Cruz, Bayamón, 00961, Puerto Rico
CDT Grupo Médico San Pablo Inc. - Puerto Rico
Recruiting
Cll Santa Cruz, Bayamón, 00961, Puerto Rico
Instituto De Neurología Dra. Ivonne Fraga - Puerto Rico
Recruiting
708 Av. Juan Ponce de León #102, San Juan, 00918, Puerto Rico
Barbara Diaz Hernandez MD Research Inc. - Puerto Rico
Recruiting
1704 Av. Paraná #2, San Juan, 00926, Puerto Rico
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