Last updated 8 months ago
Clinical Trial of Aesculus Hippocastanum and Associations Versus Diosmina and Hesperidina in Chronic Venous Insuficiency
120 patients around the world
Available in Brazil
Phlebotonics represent a heterogeneous group of therapeutic products of natural or
synthetic origin that exhibit effects on edema and/or symptoms related to chronic venous
diseaseThis class of drugs is effective in improving the symptoms of chronic venous
insufficiency and in cases of hemorrhoids and for this reason they have become an
established component of the therapeutic arsenal for all phases of these diseases
Phlebotomics are classified into four categories: benzopyrones, saponins, other plant
extracts, and synthetic drugs
Fundação Educacional Serra dos Órgãos
1Research sites
120Patients around the world
This study is for people with
Venous disorders
Chronic Venous Insufficiency
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Patient presenting CEAP classification from grade C0 to C3 in the evaluation of venous disease of the lower limbs.Clinical symptoms of chronic venous insufficiency of the lower limbs, defined by the 100mm visual scale performed by the patient between 20mm and 60mm in the most symptomatic lower limb.For female patients of reproductive age, not pregnant or breastfeeding, using reliable contraceptives.Patient read, understood, signed and dated the free and informed consent form.
- Treatment with compression stockings within 2 months of study inclusion date.Treatment with venotonics within 2 months of the date of inclusion in the study.Women of reproductive age who are pregnant or breastfeeding, or who do not wish to use contraception during the study period.Known allergy or hypersensitivity to any component of the study drug.Known significant laboratory abnormality.CEAP Grade Assessment of level 4, 5, or 6.Patient with venous disease requiring intravenous chemical surgery/sclerotherapy.Patient presenting with a painful pathology in addition to venous pain in the lower limbs.Patient with a history of thrombosis or thromboembolic disease within 6 months of the date of inclusion in the study.Patient with a change in general condition that is incompatible with his/her participation in the study.Patient who wishes to become pregnant within 6 months.
Sites
UNIFESO - Centro Universitário Serra dos Órgãos
Recruiting
SponsorFundação Educacional Serra dos Órgãos
Conditions
Chronic Venous Insufficiency
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT06579482
