Last updated 2 months ago
A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes
1500 patients around the world
Available in Puerto Rico, United States, Argentina, Brazil
Eli Lilly and Company
11Research sites
1500Patients around the world
This study is for people with
Obesity
Diabetes
Diabetes mellitus type 2
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Have a body mass index (BMI) ≥27.0 kilogram/square meter (kg/m²).Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight.Have a diagnosis of Type 2 Diabetes (T2D), with HbA1c ≥7% (≥53 mmol/mol) to ≤10% (86 mmol/mol) and are on stable treatment for T2D for at least 90 days prior to screening, consisting of: either diet/exercise alone or up to 3 oral antihyperglycemic medications (excluding dipeptidyl peptidase IV inhibitors (DPP-4i) or glucagon-like peptide-1 (GLP-1) receptor agonists (RA).
- Have Type 1 Diabetes (T1D), history of ketoacidosis or hyperosmolar state/coma, or any other types of diabetes except T2D.Have a self-reported change in body weight >5 kg (11 pounds) within 90 days prior to screening.Are currently receiving or planning to receive treatment for diabetic retinopathy and/or macular edema (for example, laster photocoagulation or intravitreal injections of anti-vascular endothelial growth factor inhibitors).Have family (first-degree relative) or personal history of medullary thyroid cancer (MTC) or multiple endocrine neoplasia 2 (MEN2) syndrome.Have had a history of chronic or acute pancreatitis.
Sites
Instituto de Investigaciones Clínicas Tucumán
Recruiting
Instituto Centenario
Recruiting
Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Médica - Rosario, Santa Fe
Recruiting
Instituto de Investigaciones Clínicas (IIC) - Rosario
Recruiting
Sanatorio San Martin
Recruiting
Clínica Universitaria Privada Reina Fabiola - Córdoba
Recruiting
Centro de Diagnóstico y Rehabilitación - CEDIR
Recruiting
Centro Diabetológico y Nutricional (CEMEDIAB)
Recruiting
Mautalen - Salud e Investigación - CABA
Recruiting
CONEXA Investigación Clínica S.A.
Recruiting
StudyATTAIN-2
SponsorEli Lilly and Company
Study typeInterventional
Conditions
ObesityDiabetes mellitus type 2
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT05872620
